Endocrine Abstracts

Context: Recent studies showed a high prevalence of anxiety and depressive symptoms in patients with primary hyperaldosteronism (PA). A cross-sectional analysis suggested only minor improvement following adrenalectomy (ADX) and mineralocorticoidreceptor antagonist (MRA) therapy.Objective: Our aim was to determine the course of anxiety and depression in untreated patients.Design: We investigated 15 patients with PA at time of diagno...

Recent studies indicating that normokaliemic primary aldosteronism (PA) is a more frequent cause of hypertension than previously expected led to an increased interest in biochemical screening strategies. We investigated biochemical diagnostic strategies used in different academic centres for patients documented in the German National Conn’s Registry. Data from 7 centres in 5 cities have been entered into a database by trained personnel. For analysis, results from 522 pati...

Objectives: The TNM classification is a worldwide benchmark for reporting the extent of malignant disease and is intended as a prognostic tool to predict the outcome in patients with cancer. Until 2004, no TNM classification was available for adrenocortical carcinoma (ACC) and different staging systems were used. Due to the rarity of this malignancy, the prognostic value of different staging systems has never been compared directly in a large series of patients.<p class="a...